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HRID3463

反应详情

EQUATION

反应方程式

HRID 3463 的结构方程式

REACTANTS

反应物

3
结构：N
HCID222

Ammonia gas

H3N

结构：CC(C)(C)N=C=O
HCID62412

tert-Butyl isocyanate

C5H9NO

结构：Cc1ccccc1-c1cc2cnc(N)nc2nc1N
HCID21850031

未命名化合物

PRODUCTS

生成物

1
结构：Cc1ccccc1-c1cc2cnc(N)nc2nc1NC(=O)NC(C)(C)C
HCID5329118

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C
溶剂HCID297

Methane

CH4

PROCEDURE

实验过程

The title compound was prepared from 6-o-tolyl-pyrido[2,3-d]pyrimidine-2,7-diamine from Example 90 and tert-butyl isocyanate according to Example 2. The product was purified by MPLC eluting with CHCl3 :EtOAc (1:1) afford the pure product; mp 195°-197° C., CIMS (1% ammonia in methane): m/z (relative intensity) 351 (MH+ +1, 55), 352 (MH+ +2, 12), 84 (100).

WORKUP

后处理

  1. customThe product was purified by MPLC
  2. washeluting with CHCl3 :EtOAc (1:1)
  3. customafford the pure product