huagongshe.com
HRID346416

反应详情

EQUATION

反应方程式

HRID 346416 的结构方程式

REACTANTS

反应物

2
结构：Nc1cc(Cl)c(Cl)cc1F
HCID223091

4,5-dichloro-2-fluoroaniline

C6H4Cl2FN

结构：O=[N+]([O-])c1cc2c(Cl)ncnc2cc1F
HCID10609358

4-Chloro-7-fluoro-6-nitroquinazoline

C8H3ClFN3O2

PRODUCTS

生成物

1
结构：O=[N+]([O-])c1cc2c(Nc3cc(Cl)c(Cl)cc3F)ncnc2cc1F
HCID11176185

未命名化合物

收率 78%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(C)O
溶剂HCID3776

Isopropanol

C3H8O

PROCEDURE

实验过程

3,4-Dichloro-6-fluoroaniline (1 equivalent) was reacted with 4-chloro-7-fluoro-6-nitroquinazoline (3.5 equivalents), in iso-propylalcohol. After filtration, 4-[(3,4-dichloro-6-fluorophenyl)amino]-7-fluoro-6-nitroquinazoline was obtained in 78% yield.

WORKUP

后处理

  1. filtrationAfter filtration