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HRID346729

反应详情

EQUATION

反应方程式

HRID 346729 的结构方程式

REACTANTS

反应物

2
结构：Cc1ccc(S(=O)(=O)Cl)cc1
HCID7397

p-Toluenesulfonyl chloride

C7H7ClO2S

结构：CC(C)(C)OC(=O)N1CCN(c2ccc(N)c(NS(=O)(=O)c3ccccc3)c2)CC1
HCID22272479

未命名化合物

PRODUCTS

生成物

1
结构：Cc1ccc(S(=O)(=O)Nc2ccc(N3CCNCC3)cc2NS(=O)(=O)c2ccccc2)cc1
HCID10228031

未命名化合物

PROCEDURE

实验过程

4-Methyl-N-[2-[(phenylsulfonyl)amino]-4-(1-piperazinyl)phenyl]benzenesulfonamide was synthesized from N-{2-amino-5-(4-t-butyloxycarbonyl-piperazinyl)-phenyl}benzenesulfonamide and p-toluenesulfonylchloride (46 mg, 0.239 mmol) according to general method 3 to give 70 mg of a purple solid. MS (posES-FIA) m/z=Found: 487.2; Calcd: 487.14; 1H-NMR δ 7.73–7.45 (m, 7H), 7.26 (d, 2H), 6.74 (s, 1H), 6.62–6.60 (m, 2H), 3.69 (app t, 2H), 3.39 (app t, 2H), 3.29–3.74 (m, 4H), 2.38 (s, 3H).