Cyclohexene → HCID 21082866, compound

HRID 347588Notes

Reaction equation

HRID 347588 reaction equation
[Cl:1][C:2]1[C:7]([N+:8]([O-])=O)=[CH:6][C:5]([N+:11]([O-])=O)=[CH:4][N:3]=1.[NH:14]1[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1.[H][H].C1CCCCC=1>C(O)C.[Pd]>[ClH:1].[ClH:1].[NH2:8][C:7]1[C:2]([N:14]2[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]2)=[N:3][CH:4]=[C:5]([NH2:11])[CH:6]=1

Participants

7

Reactant 4

HCID 8079CyclohexeneHCID 8082PiperidineHCID 757382-Chloro-3,5-dinitropyridineHCID 178418361HCID 178418361, compound

Product 1

HCID 21082866HCID 21082866, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

2 g of (1-piperidyl)-3,5-dinitropyridine, obtained according to Protocol A from 2-chloro-3,5-dinitropyridine and piperidine, were reduced by hydrogen transfer in 50 ml of ethanol in the presence of palladium-on-charcoal and 5 ml of cyclohexene. 930 mg of N-(3,5-diaminopyrid-2-yl)piperidine dihydrochloride were thus obtained.

Sources & evidence

ORD record
ord-03c5eb8df3444a068ca7ef4870414a09
Source dataset
uspto-grants-2007_02
Patent number
US07175670B2

Reaction notes

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