2-Chloro-3,5-dinitropyridine → HCID 21082859, compound

HRID 347590Notes

Reaction equation

HRID 347590 reaction equation
Cl[C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([N+:11]([O-:13])=[O:12])=[CH:4][N:3]=1.[CH2:14]([N:16]1[CH2:21][CH2:20][NH:19][CH2:18][CH2:17]1)[CH3:15]>C1COCC1>[CH2:14]([N:16]1[CH2:21][CH2:20][N:19]([C:2]2[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([N+:11]([O-:13])=[O:12])=[CH:4][N:3]=2)[CH2:18][CH2:17]1)[CH3:15]

Participants

4

Reactant 2

HCID 757382-Chloro-3,5-dinitropyridineHCID 791961-Ethylpiperazine

Product 1

HCID 21082859HCID 21082859, compoundYield 120.9%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Conditions

Temperature
60 °C

Procedure

3 g (14.7 mmol) of 2-chloro-3,5-dinitropyridine, 20 ml of THF and 30 mmol of 4-ethylpiperazine were placed in a round-bottomed flask. The mixture was maintained at 60° C. for two hours with stirring and was then poured into a mixture of ice-water with stirring. The precipitate formed was filtered off by suction and dried under vacuum to constant weight. 5 g of yellow powder were obtained.

Workup

  1. stirringwith stirring
  2. customThe precipitate formed
  3. filtrationwas filtered off by suction
  4. customdried under vacuum to constant weight

Sources & evidence

ORD record
ord-fb9c77676d274d95a1ef089459854c46
Source dataset
uspto-grants-2007_02
Patent number
US07175670B2

Reaction notes

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