2-Chloro-3,5-dinitropyridine → HCID 23064287, compound

HRID 347591Notes

Reaction equation

HRID 347591 reaction equation
Cl[C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([N+:11]([O-:13])=[O:12])=[CH:4][N:3]=1.[CH3:14][CH:15]1[CH2:20][CH:19]([CH3:21])[CH2:18][NH:17][CH2:16]1>C1COCC1>[CH3:14][CH:15]1[CH2:20][CH:19]([CH3:21])[CH2:18][N:17]([C:2]2[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([N+:11]([O-:13])=[O:12])=[CH:4][N:3]=2)[CH2:16]1

Participants

4

Reactant 2

HCID 757382-Chloro-3,5-dinitropyridineHCID 1182593,5-Dimethylpiperidine

Product 1

HCID 23064287HCID 23064287, compoundYield 92.6%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Conditions

Temperature
60 °C

Procedure

2 g (9.82 mmol) of 2-chloro-3,5-dinitropyridine, 10 ml of THF and 20 mmol of 3,5-dimethylpiperidine were placed in a round-bottomed flask. he mixture was maintained at 60° C. for 15 hours with stirring and was then poured into a mixture of ice-water with stirring. The precipitate formed was filtered off by suction and dried under vacuum to constant weight. 2.55 g of yellow powder were obtained.

Workup

  1. stirringwith stirring
  2. customThe precipitate formed
  3. filtrationwas filtered off by suction
  4. customdried under vacuum to constant weight

Sources & evidence

ORD record
ord-c5604fbac0454a1ca930229f44255f72
Source dataset
uspto-grants-2007_02
Patent number
US07175670B2

Reaction notes

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