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HRID347646

反应详情

EQUATION

反应方程式

HRID 347646 的结构方程式

REACTANTS

反应物

2
结构：CCI
HCID6340

Ethane, iodo-

C2H5I

结构：O=C1CCNc2ccccc2N1
HCID223771

1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one

C9H10N2O

PRODUCTS

生成物

1
结构：CCN1C(=O)CCNc2ccccc21
HCID3078200

2H-1,5-Benzodiazepin-2-one, 1,3,4,5-tetrahydro-1-ethyl-

C11H14N2O

PROCEDURE

实验过程

2-Oxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine (1.95 g, 11.96 mmol) was reacted with ethyl iodide (1.4 ml, 17.5 mmol) according to the procedure in Example 18A. The product was purified by flash chromatography on silica (eluant EtOAc); yield 1.70 g (75%).

WORKUP

后处理

  1. customThe product was purified by flash chromatography on silica (eluant EtOAc)