Potassium Iodide → HCID 21091175, compound

HRID 351219Notes

Reaction equation

HRID 351219 reaction equation
[CH3:1][C:2]([C:4]1[CH:5]=[CH:6][C:7]([OH:10])=[CH:8][CH:9]=1)=[O:3].[C:11]([O:15][C:16]([NH:18][CH2:19][CH2:20]Br)=[O:17])([CH3:14])([CH3:13])[CH3:12].[I-].[K+].C(=O)([O-])[O-].[K+].[K+]>CN(C)C=O>[C:2]([C:4]1[CH:9]=[CH:8][C:7]([O:10][CH2:20][CH2:19][NH:18][C:16](=[O:17])[O:15][C:11]([CH3:14])([CH3:13])[CH3:12])=[CH:6][CH:5]=1)(=[O:3])[CH3:1]

Participants

6

Reactant 4

HCID 4875Potassium IodideHCID 74694'-HydroxyacetophenoneHCID 11430Potassium CarbonateHCID 4103526tert-Butyl N-(2-bromoethyl)carbamate

Product 1

HCID 21091175HCID 21091175, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

To a solution of 4-hydroxyacetophenone (10 g) and 2-tert-butoxycarbonylaminoethylbromide (24.7 g) in N,N-dimethylformamide (50 ml) was added potassium iodide (12.2 g) and potassium carbonate (15.2 g).

Sources & evidence

ORD record
ord-3f8c5077f99d4754a3bc2471d79b3252
Source dataset
uspto-grants-2007_02
Patent number
US07183306B2

Reaction notes

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