Methyl Acrylate → HCID 21872426, compound

HRID 351486Notes

Reaction equation

HRID 351486 reaction equation
[C:1]([O:5][CH3:6])(=[O:4])[CH:2]=[CH2:3].[CH3:7][O:8][CH2:9][CH2:10][NH2:11].[C:12](#[N:15])[CH:13]=[CH2:14]>>[C:12]([CH2:13][CH2:14][N:11]([CH2:10][CH2:9][O:8][CH3:7])[CH2:3][CH2:2][C:1]([O:5][CH3:6])=[O:4])#[N:15]

Participants

4

Reactant 3

HCID 7294Methyl AcrylateHCID 7855AcrylonitrileHCID 80182-Methoxyethylamine

Product 1

HCID 21872426HCID 21872426, compound

Conditions

Temperature
70 °C

Procedure

At 20 to 30° C., 11.4 g of methyl acrylate was added to 10.0 g of 2-methoxyethylamine, which was allowed to stand for 2 hours. Then 15.0 g of acrylonitrile was added to the reaction solution, which was heated at 70° C. for 20 hours. Vacuum concentration yielded methyl N-(2-cyanoethyl)-N-(2-methoxyethyl)-3-aminopropionate.

Workup

  1. concentrationVacuum concentration

Sources & evidence

ORD record
ord-6528482e55c843fd90a82f7c2d43b3a5
Source dataset
uspto-grants-2004_06
Patent number
US06743564B2

Reaction notes

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