反应详情

1 g (2.36 mmol) of 18 are dissolved in 20 ml of dichloromethane and stirred at room temperature for 20 hours with 2 ml of trifluoroacetic acid. The solution is subsequently evaporated, and the residue is purified by preparative HPLC on RP-18, giving ethyl 3-phenyl-3-(6-carboxymethoxyindol-3-yl)-propionate trifluoroacetate.

1. customThe solution is subsequently evaporated
2. customthe residue is purified by preparative HPLC on RP-18