反应详情

In 1N hydrochloric acid (100 ml), the resulting ethyl 4-amidinobenzoate hydrochloride (3.00 g) was dissolved at room temperature, followed by heating under reflux for 2 hours. The solvent was then distilled off under reduced pressure. Colorless crystalline powder so precipitated was collected by filtration and washed with a small amount of tetrahydrofuran, whereby the title compound (2.69 g, 94%) was obtained.

1. temperatureby heating
2. temperatureunder reflux for 2 hours
3. distillationThe solvent was then distilled off under reduced pressure
4. customColorless crystalline powder so precipitated
5. filtrationwas collected by filtration
6. washwashed with a small amount of tetrahydrofuran, whereby the title compound (2.69 g, 94%)
7. customwas obtained