Hydrochloric Acid → HCID 54515481, compound

HRID 352865Notes

Reaction equation

HRID 352865 reaction equation
[O:1]1[CH:5]=[CH:4][C:3]([CH:6]=O)=[CH:2]1.[N+:8]([CH3:11])([O-:10])=[O:9].[OH-].[Na+].Cl>C(O)C>[O:1]1[CH:5]=[CH:4][C:3]([CH:6]=[CH:11][N+:8]([O-:10])=[O:9])=[CH:2]1

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 6375NitromethaneHCID 103513-FuraldehydeHCID 14798Sodium Hydroxide

Product 1

HCID 54515481HCID 54515481, compoundYield 55.3%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of 3-furaldehyde (10.0 g) in ethanol (200 ml), nitromethane (6.37 g) was added at room temperature, followed by the dropwise addition of a 10N-aqueous sodium hydroxide solution (11.0 ml) at 0° C. The resulting mixture was stirred for 1 hour. The reaction mixture was poured into a 15% aqueous solution of hydrochloric acid (500 ml). The precipitate so formed was collected by filtration and dried, whereby the title compound (8.01 g) was obtained as a yellowish white solid.

Workup

  1. customThe precipitate so formed
  2. filtrationwas collected by filtration
  3. customdried

Sources & evidence

ORD record
ord-6df9b58382bb4c75860588fb268340d2
Source dataset
uspto-grants-2004_06
Patent number
US06747023B1

Reaction notes

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