Diethanolamine → HCID 11042091, compound

HRID 353521Notes

Reaction equation

HRID 353521 reaction equation
[NH:1]([CH2:5][CH2:6][OH:7])[CH2:2][CH2:3][OH:4].[F:8][C:9]1[CH:16]=[CH:15][C:12]([CH2:13]Cl)=[CH:11][CH:10]=1>>[F:8][C:9]1[CH:16]=[CH:15][C:12]([CH2:13][N:1]([CH2:5][CH2:6][OH:7])[CH2:2][CH2:3][OH:4])=[CH:11][CH:10]=1

Participants

3

Reactant 2

HCID 8113DiethanolamineHCID 96024-Fluorobenzyl chloride

Product 1

HCID 11042091HCID 11042091, compound

Procedure

2-[(4-Fluoro-benzyl)-(2-hydroxy-ethyl)-amino]-ethanol was prepared according to the general method as outlined in Example 1 (Step 4). Starting from diethanolamine (15.7 g, 150 mmol), and 4-fluoro-benzyl chloride (14.4 g, 100 mmol) 20 g of the product was isolated. Yield 20 g, (93%%); yellow oil; MS: 215 (M+)+.

Workup

  1. customwas isolated

Sources & evidence

ORD record
ord-58a3b1aa65104886b3a032811768c39d
Source dataset
uspto-grants-2004_06
Patent number
US06753337B2

Reaction notes

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