反应详情

60.0 gm (0.2 mol) of 5-(3-chloro-propionyl)-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one and 42.5 gm (0.5 mol) of piperidine were refluxed in 600 ml of isopropanol and worked up as described in Example 1. 53 gm of the hydrochloride (recrystallized from n-propanol), m.p. 250°-252° C., were obtained