Hydrochloric Acid → HCID 15341898, compound

HRID 354914Notes

Reaction equation

HRID 354914 reaction equation
O1CCCCC1[O:7][C@H:8]1[CH2:13][CH2:12][C@H:11]2[C@H:14]3[C@H:24]([CH2:25][CH2:26][C@:9]12[CH3:10])[C@:22]1([CH3:23])[C@H:17]([C:18](=[O:27])[CH2:19][CH2:20][CH2:21]1)[CH2:16][CH2:15]3.Cl>C(O)C>[OH:7][C@H:8]1[CH2:13][CH2:12][C@H:11]2[C@H:14]3[C@H:24]([CH2:25][CH2:26][C@:9]12[CH3:10])[C@:22]1([CH3:23])[C@H:17]([C:18](=[O:27])[CH2:19][CH2:20][CH2:21]1)[CH2:16][CH2:15]3

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 1534189717beta-Tetrahydropyranyloxy-5alpha-androstan-4-one

Product 1

HCID 15341898HCID 15341898, compoundYield 116.7%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To 75 ml of ethanol is added 2.32 g of the product of Step E to form a solution which is then treated with 5 ml of 2.5 N hydrochloric acid and warmed on a steam bath for 40 min. to yield 2.1 g of a crystalline product having a m.p. of 123°-126° C.

Workup

  1. customto form a solution which
  2. temperaturewarmed on a steam bath for 40 min.

Sources & evidence

ORD record
ord-7add9fb1d282489394e78ccb92ff4e39
Source dataset
uspto-grants-1983_03
Patent number
US04377584

Reaction notes

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