4,7-Dichloroquinoline → HCID 14837824, compound

HRID 355388Notes

Reaction equation

HRID 355388 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][C:8]([Cl:12])=[CH:9][CH:10]=2)[N:5]=[CH:4][CH:3]=1.[NH:13]1[CH:17]=[N:16][CH:15]=[N:14]1>CN(C)C=O>[N:13]1([C:2]2[C:11]3[C:6](=[CH:7][C:8]([Cl:12])=[CH:9][CH:10]=3)[N:5]=[CH:4][CH:3]=2)[CH:17]=[N:16][CH:15]=[N:14]1

Participants

4

Reactant 2

HCID 68664,7-DichloroquinolineHCID 92571H-1,2,4-Triazole

Product 1

HCID 14837824HCID 14837824, compoundYield 112.8%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

1.98 g of 4,7-dichloro-quinoline and 1.38 g of 1H-1,2,4-triazole are reacted in 10 ml of dimethyl formamide and worked up as described in Example 1. 2.6 g of 4-(1H-1,2,4-triazole-1-yl)-7-chloro-quinoline (Substance 2) are obtained.

Sources & evidence

ORD record
ord-5c6abf28f5aa4044bac2fad78fab0e2d
Source dataset
uspto-grants-1998_11
Patent number
US05830903

Reaction notes

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