Piperidine → HCID 18940154, compound

HRID 355603Notes

Reaction equation

HRID 355603 reaction equation
[N:1]1([C:7]2[C:12]3[O:13][C:14]4[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=4[C:11]=3[C:10](=O)[C:9](=[O:21])[CH:8]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.Cl.[NH2:23][OH:24].N1CCCCC1>CO>[OH:21][C:9]1[CH:8]=[C:7]([N:1]2[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]2)[C:12]2[O:13][C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=3[C:11]=2[C:10]=1[N:23]=[O:24]

Participants

5

Reactant 3

HCID 8082PiperidineHCID 443297Hydroxyamine hydrochlorideHCID 189401534-Piperidinodibenzofuran-1,2-dione

Product 1

HCID 18940154HCID 18940154, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

4-Piperidinodibenzofuran-1,2-dione (18.4; 0.062 mol) was added in one portion to a vigorously stirred solution of hydroxylamine hydrochloride (22.9 g; 0.33 mol) and piperidine (28 g; 0.33 mol) in methanol (230 ml) at room temperature. After 1.75 hours the mixture was filtered and the resulting solid washed with water and dried to yield 2-hydroxy-1-nitroso-4-piperidinodibenzofuran as a red-brown solid (3.48 g; 19%), m.pt. 181°-185° C. (decomp 207° C.). ##STR12##

Workup

  1. filtrationAfter 1.75 hours the mixture was filtered
  2. washthe resulting solid washed with water
  3. customdried

Sources & evidence

ORD record
ord-ea0960e6d31b47338084fa682206cf1e
Source dataset
uspto-grants-1998_11
Patent number
US05833885

Reaction notes

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