Phthalimide potassium salt → Phthalimide

HRID 355618Notes

Reaction equation

HRID 355618 reaction equation
[C:1]1(=[O:11])[NH:5][C:4](=[O:6])[C:3]2=[CH:7][CH:8]=[CH:9][CH:10]=[C:2]12.[K]>CN(C)C=O>[C:1]1(=[O:11])[NH:5][C:4](=[O:6])[C:3]2=[CH:7][CH:8]=[CH:9][CH:10]=[C:2]12

Participants

3

Reactant 1

HCID 24194345Phthalimide potassium salt

Product 1

HCID 6809Phthalimide

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Conditions

Temperature
50 °C

Procedure

To a 250 round bottom flask fitted with a condenser, nitrogen inlet and an overhead stirrer (IKA), was added 6 grams of chloromethyl paramagnetic beads prepared as in Example 2, 100 ml of dimethylformamide and 1.2 grams (6.4 mmole) potassium phthalimide and mixture stirred at 50° C. for 20 hours. At the end of 20 hours, the product was washed with dimethylformamide, methanol, water and ethanol and then dried under vacuum to provide phthalimide incorporated beads.

Workup

  1. customTo a 250 round bottom flask fitted with a condenser, nitrogen inlet and an overhead stirrer (IKA)
  2. additionwas added
  3. washAt the end of 20 hours, the product was washed with dimethylformamide, methanol, water and ethanol
  4. customdried under vacuum

Sources & evidence

ORD record
ord-dd2d5a529c294e10b2524a04ac70943c
Source dataset
uspto-grants-1998_11
Patent number
US05834121

Reaction notes

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