Hydrochloric Acid → HCID 73472963, compound

HRID 357067Notes

Reaction equation

HRID 357067 reaction equation
[C:1]1([CH2:7][CH2:8][CH2:9][CH:10]=[C:11]2[S:15][C:14](=[O:16])[N:13]([CH2:17][CH2:18][CH2:19][CH2:20][S:21][C:22]3[N:27]4[CH:28]=[CH:29][N:30]=[C:26]4[CH:25]=[CH:24][CH:23]=3)[C:12]2=[O:31])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[ClH:32]>CO>[ClH:32].[C:1]1([CH2:7][CH2:8][CH2:9][CH:10]=[C:11]2[S:15][C:14](=[O:16])[N:13]([CH2:17][CH2:18][CH2:19][CH2:20][S:21][C:22]3[N:27]4[CH:28]=[CH:29][N:30]=[C:26]4[CH:25]=[CH:24][CH:23]=3)[C:12]2=[O:31])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 57004843HCID 57004843, compound

Product 1

HCID 73472963HCID 73472963, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of 1.56 g (3.45 mmol) of 5-(4-phenyl-butylidene)-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione in 50 ml of methanol, 0.4 ml of concentrated hydrochloric acid was added. After the solvent was distilled off, the residue was washed with diethyl ether to yield 1.47 g (87%, light yellow foamy substance) of the desired product.

Workup

  1. distillationAfter the solvent was distilled off
  2. washthe residue was washed with diethyl ether

Sources & evidence

ORD record
ord-68ea1383f5e046b482049d2ad50eba15
Source dataset
uspto-grants-1998_11
Patent number
US05840732

Reaction notes

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