3-Mercaptopropionic Acid → HCID 70508087, compound

HRID 358050Notes

Reaction equation

HRID 358050 reaction equation
[NH:1]([C:5]1[CH:6]=[CH:7][C:8]([NH2:20])=[C:9]([CH:19]=1)[CH:10](O)[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[Cl:17])C(C)=O.[SH:21][CH2:22][CH2:23][C:24]([OH:26])=[O:25]>Cl>[ClH:17].[ClH:17].[NH2:20][C:8]1[CH:7]=[CH:6][C:5]([NH2:1])=[CH:19][C:9]=1[CH:10]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[Cl:17])[S:21][CH2:22][CH2:23][C:24]([OH:26])=[O:25]

Participants

4

Reactant 2

HCID 65143-Mercaptopropionic AcidHCID 20449999HCID 20449999, compound

Product 1

HCID 70508087HCID 70508087, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

107.3 g of 5-acetamino-2-amino-2'-chlorobenzhydrol are heated to 90° for 1 hour together with 36.8 g of 3-mercaptopropionic acid in 290 ml of 6N hydrochloric acid. After cooling, the crystals are filtered off. There is obtained 3-[(2,5-diaminophenyl)(2-chlorophenyl)methylthio]propionic acid dihydrochloride of melting point 234°-235° (decomposition).

Workup

  1. temperatureAfter cooling
  2. filtrationthe crystals are filtered off

Sources & evidence

ORD record
ord-38f309781e714ac19cdbd5258f539c6b
Source dataset
uspto-grants-1984_08
Patent number
US04464300

Reaction notes

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