反应详情

A mixture of 2-[2-(N-methylformamido)phenyl]-2oxoethyl benzoate (84 g), potassium carbonate (39.2 g) and dry dimethylformamide (1100 ml) was stirred at 50 to 60° for 4 hours. The solvent was removed under reduced pressure at 60° and the residue was triturated with water (700 ml). The resultant solid was collected by filtration and washed with water (4×250 ml) followed by diethyl ether (250 ml) to give the novel compound 1-methyl-4-oxo-1,4-dihydroquinol-3-yl benzoate, m.p.2)5-21 7°.

1. customThe solvent was removed under reduced pressure at 60°
2. customthe residue was triturated with water (700 ml)
3. filtrationThe resultant solid was collected by filtration
4. washwashed with water (4×250 ml)