Potassium Carbonate → HCID 53903610, compound

HRID 358689Notes

Reaction equation

HRID 358689 reaction equation
[C:1]([O:9][CH2:10][C:11]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[N:19]([CH2:22][CH3:23])[CH:20]=O)=[O:12])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(=O)([O-])[O-].[K+].[K+]>CN(C)C=O>[C:1]([O:9][C:10]1[C:11](=[O:12])[C:13]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[N:19]([CH2:22][CH3:23])[CH:20]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 11430Potassium CarbonateHCID 23128147HCID 23128147, compound

Product 1

HCID 53903610HCID 53903610, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A mixture of 2-[2-(N-ethylformamido)phenyl]-2- C oxoethyl benzoate (21.2 g), potassium carbonate (11.82 g) and dry dimethylformamide (330 ml) was stirred at 60° for 15 hours. The reaction mixture was filtered and the residue washed with dimethylformamide (150 ml). The combined filtrate and washings were evaporated under reduced pressure at 60° and the residue triturated with water (200 ml) and then with acetone (2×30 ml) to give the novel compound 1-ethyl-4-oxo-1,4-dihydroquinol-3-yl benzoate, m.p. 190°-192°.

Workup

  1. filtrationThe reaction mixture was filtered
  2. washthe residue washed with dimethylformamide (150 ml)
  3. customThe combined filtrate and washings were evaporated under reduced pressure at 60°
  4. customthe residue triturated with water (200 ml)

Sources & evidence

ORD record
ord-778d76bef52c4ef8b935dfd832e5a800
Source dataset
uspto-grants-1991_03
Patent number
US04997840

Reaction notes

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