Oxalyl chloride → HCID 14580088, compound

HRID 358951Notes

Reaction equation

HRID 358951 reaction equation
[C:1]([O:4][C:5]1[C:6]([CH3:20])=[C:7]([CH3:19])[C:8]2[O:12][CH:11]([CH2:13][C:14](O)=[O:15])[CH2:10][C:9]=2[C:17]=1[CH3:18])(=[O:3])[CH3:2].C(Cl)(=O)C([Cl:24])=O>C1C=CC=CC=1>[C:1]([O:4][C:5]1[C:6]([CH3:20])=[C:7]([CH3:19])[C:8]2[O:12][CH:11]([CH2:13][C:14]([Cl:24])=[O:15])[CH2:10][C:9]=2[C:17]=1[CH3:18])(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 65578Oxalyl chlorideHCID 65961[5-(Acetyloxy)-4,6,7-trimethyl-2,3-dihydro-1-benzofuran-2-yl]acetic acid

Product 1

HCID 14580088HCID 14580088, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

To a suspension of (RS)-2-(2,3-dihydro-5-acetyloxy-4,6,7-trimethylbenzofuranyl) acetic acid (see example 2) (4.4 g) in benzene (36 ml) is added dropwise oxalyl chloride (7 ml) over 30'.

Sources & evidence

ORD record
ord-52188ab80e9b4b34b4c1a803b10ee522
Source dataset
uspto-grants-1991_03
Patent number
US04999350

Reaction notes

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