Triphenylphosphine → HCID 10536182, compound

HRID 358961Notes

Reaction equation

HRID 358961 reaction equation
[CH:1]([N:4]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[N+:7]([O-])=[C:6]([OH:15])[C:5]1=[O:16])([CH3:3])[CH3:2].C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1>CN(C)C=O>[CH:1]([N:4]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[NH:7][C:6](=[O:15])[C:5]1=[O:16])([CH3:3])[CH3:2]

Participants

4

Reactant 2

HCID 11776TriphenylphosphineHCID 178456567HCID 178456567, compound

Product 1

HCID 10536182HCID 10536182, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A solution of 3,4-dihydro-4-isopropyl-2-hydroxy-3-oxo-quinoxaline-1-oxid (15.5 g, 0.07 mole) and triphenylphosphine (26.2 g, 0.1 mole) in dimethylformamide (DMF) (100 ml) was stirred at 120° C. for 12 hours, whereafter the solvent was evaporated in vacuo. The residue was stirred in methylene chloride (150 ml) whereby the formed triphenyl phosphine oxid was dissolved. The product was then collected as pale crystals by filtration followed by wash with methylene chloride M.p. 227°-228° C.

Workup

  1. customwas evaporated in vacuo
  2. dissolutionwas dissolved
  3. filtrationThe product was then collected as pale crystals by filtration
  4. washby wash with methylene chloride M.p. 227°-228° C.

Sources & evidence

ORD record
ord-a229aa8ecc8047088342ae2947bed48c
Source dataset
uspto-grants-1991_03
Patent number
US04999354

Reaction notes

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