Benzene → (2S)-2-hydroxy-4-phenylbutanenitrile

HRID 359917노트

반응식

HRID 359917 반응식
[C:1]([CH:3]([OH:12])[CH2:4][CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)#[N:2].C1C=CC=CC=1.C(O)C>Cl>[C:1]([C@@H:3]([OH:12])[CH2:4][CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)#[N:2]

참가 물질

5

반응물 3

HCID 241BenzeneHCID 702EthanolHCID 109098692-Hydroxy-4-phenylbutanenitrile

생성물 1

HCID 10313250(2S)-2-hydroxy-4-phenylbutanenitrile

시약·촉매·용매 1

HCID 313Hydrochloric Acid용매

실험 절차

α-Cyano-3-phenylpropyl alcohol wad hydrolyzed in concentrated hydrochloric acid (0.5 ml) at room temperature for 3 days with stirring to convert it to 1-hydroxy-4-phenyl butyric acid which was isolated by crystallization from benzene. [α]D20 =7.02° (ethanol, c=0.968).

출처 및 근거

ORD 기록
ord-f9a1eb9703f547199be743fe38b89c3a
출처 데이터셋
uspto-grants-1991_03
특허 번호
US05003083

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