反应详情

25 g of 2-methylthiocycloheptimidazole was added to 100 ml of anisole and stirred under cooling with ice. Next, 28 g of methyl trifluoromethanesulfonate was dropwise added and stirred under cooling with ice. Further, everything was stirred for 2 hours and 30 minutes at room temperature, and then, 200 ml of ethyl acetate was added, and the crystals precipitated were separated by filtration and dried. 39.7 g of a colorless crystals was obtained.

1. temperatureunder cooling with ice
2. stirringstirred
3. temperatureunder cooling with ice
4. stirringFurther, everything was stirred for 2 hours and 30 minutes at room temperature
5. customthe crystals precipitated
6. customwere separated by filtration
7. customdried