反应详情

温度

150 °C

A mixture of aniline (100 parts), 2-heptanone (220 parts), 4-toluene sulphonic acid (6 parts) and 3% palladium on carbon (5 parts) in a 1 litre autoclave was charged with hydrogen to a pressure of 80 atmospheres and heated at 150° C. for 40 hours. The cooled reaction mixture was diluted with ethyl acetate, filtered, washed with 1N-hydrochloric acid (6×200 parts) and water (2×200 parts), the ethyl acetate was separated and dried (MgSO4) before evaporating to leave N-(1-methylhexyl)aniline (76 parts, 37%).

1. customThe cooled reaction mixture
2. filtrationfiltered
3. washwashed with 1N-hydrochloric acid (6×200 parts) and water (2×200 parts)
4. customthe ethyl acetate was separated
5. dry with materialdried (MgSO4)
6. custombefore evaporating