HCID 67598507, compound → HCID 67598837, compound

HRID 362220Notes

Reaction equation

HRID 362220 reaction equation
[F:1][C:2]1[C:7]([C:8]#[C:9][Sn:10]([CH2:19][CH2:20][CH2:21][CH3:22])([CH2:15][CH2:16][CH2:17][CH3:18])[CH2:11][CH2:12][CH2:13][CH3:14])=[CH:6][CH:5]=[CH:4][N:3]=1>C1COCC1.CCCCCC>[F:1][C:2]1[C:7](/[CH:8]=[CH:9]\[Sn:10]([CH2:11][CH2:12][CH2:13][CH3:14])([CH2:19][CH2:20][CH2:21][CH3:22])[CH2:15][CH2:16][CH2:17][CH3:18])=[CH:6][CH:5]=[CH:4][N:3]=1

Participants

4

Reactant 1

HCID 67598507HCID 67598507, compound

Product 1

HCID 67598837HCID 67598837, compoundYield 83.5%

Reagents, catalysts & solvents 2

HCID 8028TetrahydrofuranSolventHCID 8058HexaneSolvent

Procedure

To a suspension of Cp2ZrHCl (2.58 g) in dry THF (50 mL) was added 2-fluoro-3-(tributylstannylethynyl)pyridine (2.05 g). After 2 hours the mixture was diluted with hexane and filtered through a short silica gel column. Evaporation of the solvents gave Z-2-fluoro-3-(2-tributylstannylethenyl)pyridine as an oil (1.72 g).

Workup

  1. filtrationfiltered through a short silica gel column
  2. customEvaporation of the solvents

Sources & evidence

ORD record
ord-6757c9f895f747f8992d675ec6608380
Source dataset
uspto-grants-1999_02
Patent number
US05869482

Reaction notes

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