Thionyl Chloride → HCID 54055627, compound

HRID 362657Notes

Reaction equation

HRID 362657 reaction equation
[F:1][CH:2]([F:19])[O:3][C:4]1[N:8]([CH3:9])[N:7]=[C:6]([N:10]2[C:14]([CH3:15])=[C:13]([C:16](O)=[O:17])[CH:12]=[N:11]2)[CH:5]=1.S(Cl)([Cl:22])=O>ClCCCl>[F:1][CH:2]([F:19])[O:3][C:4]1[N:8]([CH3:9])[N:7]=[C:6]([N:10]2[C:14]([CH3:15])=[C:13]([C:16]([Cl:22])=[O:17])[CH:12]=[N:11]2)[CH:5]=1

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 54153912HCID 54153912, compound

Product 1

HCID 54055627HCID 54055627, compound

Reagents, catalysts & solvents 1

HCID 111,2-DichloroethaneSolvent

Procedure

0.2 g (3.8 mmol) 1-(5-Difluoromethoxy-1-methyl-3-pyrazolyl)-5-methyl-4-pyrazolecarboxylic acid was suspended in 30 ml 1,2-dichloroethane and 1.19 g (10.0 mmol) thionyl chloride was added at room temperature, dropwise. The mixture was heated for 1 hour under reflux and concentrated.

Workup

  1. temperatureThe mixture was heated for 1 hour
  2. temperatureunder reflux
  3. concentrationconcentrated

Sources & evidence

ORD record
ord-c5fded5ebf694bcaaae84dee4e16dfe4
Source dataset
uspto-grants-1999_02
Patent number
US05869686

Reaction notes

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