Butyl isocyanate → HCID 14031055, compound

HRID 363986Notes

Reaction equation

HRID 363986 reaction equation
[CH3:1][S:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([S:9][CH3:10])[C:4]=1[S:11]([NH2:14])(=[O:13])=[O:12].C(=O)([O-])[O-].[K+].[K+].[CH2:21]([N:25]=[C:26]=[O:27])[CH2:22][CH2:23][CH3:24]>Cl>[CH3:1][S:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([S:9][CH3:10])[C:4]=1[S:11]([NH:14][C:26]([NH:25][CH2:21][CH2:22][CH2:23][CH3:24])=[O:27])(=[O:12])=[O:13]

Participants

5

Reactant 3

HCID 8110Butyl isocyanateHCID 11430Potassium CarbonateHCID 136703682,6-Bis(methylthio)benzenesulfonamide

Product 1

HCID 14031055HCID 14031055, compoundYield 93.3%

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

A stirred suspension of 5.0 g (0.02 mol) of 2,6-bis(methylthio)benzenesulfonamide, 8.3 g (0.06 mol) potassium carbonate and 3.4 ml (0.03 mol) n-butyl isocyanate was heated at reflux for four hours. After stirring at 25° overnight, the mixture was poured into ice and 30 ml 10% HCl. The resulting precipitate was collected, washed several times with water and air dried to provide 6.5 g of the title compound, m.p. 151°-154°.

Workup

  1. temperaturewas heated
  2. temperatureat reflux for four hours
  3. customThe resulting precipitate was collected
  4. washwashed several times with water and air
  5. customdried

Sources & evidence

ORD record
ord-dc71d8dda03f46fea376685621468c6c
Source dataset
uspto-grants-1986_08
Patent number
US04604131

Reaction notes

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