反应详情

A mixture of 5.0 g of 1-chloro-6-methoxy-4-nitro-9H-xanthen-9-one, 2.58 g of [2-(diethylamino)ethyl]-hydrazine, and 3.43 ml of diisopropylethylamine in 100 ml of N,N-dimethylformamide was stirred for two hours. The mixture was evaporated to dryness and the residue was triturated with 2-propanol. The solid was collected, washed with diethylether, and dried at 60° C. in vacuo to afford the title compound, a salt with 1.0 equivalent of hydrogen chloride, mp 285°-288° C.

1. customThe mixture was evaporated to dryness
2. customthe residue was triturated with 2-propanol
3. customThe solid was collected
4. washwashed with diethylether
5. customdried at 60° C. in vacuo