Dicyclohexylamine → 3-[[4-(1-Hexenyl)benzoyl]ethoxyamino]pentanoic acid

HRID 365044Notes

Reaction equation

HRID 365044 reaction equation
Br[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].Cl.[O:12]([NH2:15])[CH2:13][CH3:14].Cl.O(N)C.C([O:22][C:23](=[O:29])[CH2:24][CH:25](I)[CH2:26][CH3:27])C.C(O[C:33](=[O:38])[CH2:34][CH2:35][CH2:36]I)C.C1(NC2CCCCC2)CCCCC1>>[CH:5]([C:4]1[CH:36]=[CH:35][C:34]([C:33]([CH2:14][CH2:13][O:12][NH:15][CH:25]([CH2:26][CH3:27])[CH2:24][C:23]([OH:22])=[O:29])=[O:38])=[CH:2][CH:3]=1)=[CH:6][CH2:7][CH2:8][CH2:9][CH3:10]

Participants

7

Reactant 6

HCID 7582DicyclohexylamineHCID 127421-BromononaneHCID 76850O-ethylhydroxylamine hydrochlorideHCID 521874O-Methylhydroxylamine hydrochlorideHCID 10890062Ethyl 4-iodobutanoateHCID 20238940Ethyl-3 iodovalerate

Product 1

HCID 570613933-[[4-(1-Hexenyl)benzoyl]ethoxyamino]pentanoic acid

Procedure

Following the procedure of Example 7 except substituting 1-bromopentane for 1-bromononane, ethoxylamine hydrochloride for methoxylamine hydrochloride and ethyl-3 iodovalerate for ethyl-4-iodobutyrate, and eliminating the addition of dicyclohexylamine, the title compound is obtained.

Sources & evidence

ORD record
ord-2ce856bda49f44488af030f641f02af4
Source dataset
uspto-grants-1986_08
Patent number
US04607053

Reaction notes

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