3-Aminophenol → HCID 18316812, compound

HRID 365234Notes

Reaction equation

HRID 365234 reaction equation
[CH2:1](Br)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7].C([O-])(O)=O.[Na+].[NH2:14][C:15]1[CH:16]=[C:17]([OH:21])[CH:18]=[CH:19][CH:20]=1>CO>[CH2:1]([NH:14][C:15]1[CH:16]=[C:17]([OH:21])[CH:18]=[CH:19][CH:20]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7]

Participants

5

Reactant 3

HCID 115683-AminophenolHCID 123691-BromoheptaneHCID 516892Sodium Bicarbonate

Product 1

HCID 18316812HCID 18316812, compoundYield 62%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

0.11 mol of n-heptyl bromide and 0.1 mol of NaHCO3 are added to 0.1 mol of m-aminophenol in 150 ml of methanol, and the mixture is refluxed for 5 h. After cooling, it is filtered and the solvent is removed in vacuo. The oil which remains is fractionated in vacuo, to give 3-(n-heptyl-amino)phenol.

Workup

  1. temperaturethe mixture is refluxed for 5 h
  2. temperatureAfter cooling
  3. filtrationit is filtered
  4. customthe solvent is removed in vacuo

Sources & evidence

ORD record
ord-98087601a2ad43deb6466435c9860b43
Source dataset
uspto-grants-2000_10
Patent number
US06126867

Reaction notes

Loading…