HRID36563

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID13140

Acrylyl chloride

C3H3ClO

HCID11805628

7-Methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepine

C10H13NOS

PRODUCTS

生成物

HCID11391024

1-(2,3-Dihydro-7-methoxy-1,4-benzothiazepin-4(5H)-yl)-2-propen-1-one

C13H15NO2S

收率 83%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID8471

Triethylamine

C6H15N

PROCEDURE

实验过程

7-Methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepine (10.0 g) (refer to preparation examples 1 to 6 as mentioned below), triethylamine (10.2 g) and acryloyl chloride (6.9 g) were reacted in the same manner as in Experimental Example 1 to give 4-acryloyl-7-methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepine (10.6 g).