反应详情

Prepared according to the method described in Example 1(e) above from (R)-N5 -(Cbz)-N2 -(diphenylacetyl)-(S)-N-(1-phenylethyl)ornithine amide (2.0 g; 3.5 mmol; from step (b) above), 10% Pd/C (w/w; 150 mg), HOAc (100 mL; instead of MeOH), overnight reaction time. The crude acetate salt was converted to the sub-title hydrochloride and was used without further purification.

1. customPrepared
2. customwas used without further purification