HRID366067
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
产物
AUXILIARIES
试剂、催化剂与溶剂
PROCEDURE
实验过程
Prepared according to the method described in Example 1(e) above from (R)-N5 -(Cbz)-N2 -(diphenylacetyl)-(S)-N-[2-hydroxy-1 -(4-methoxyphenyl)-ethyl]ornithine amide (2.85 g; from step (c) above), 10% Pd/C (1.40 g), MeOH (200 mL) and concentrated HCl (2 mL) under hydrogen for 6 hours to give the crude product as a solid (2.6 g). Pure sub-title compound was obtained by crystallization from MeOH:diethyl ether to give a white solid (1.58 g).
WORKUP
后处理
- customPrepared
- customto give the crude product as a solid (2.6 g)