2-Bromo-1-(4-hydroxyphenyl)ethanone → 138330-02-6

HRID 366450Notes

Reaction equation

HRID 366450 reaction equation
[CH:1]1[C:6]([C:7]([CH2:9][Br:10])=O)=[CH:5][CH:4]=[C:3]([OH:11])[CH:2]=1.[C:12]([NH2:15])(=[S:14])[CH3:13]>C(Cl)Cl>[BrH:10].[CH3:13][C:12]1[S:14][CH:9]=[C:7]([C:6]2[CH:5]=[CH:4][C:3]([OH:11])=[CH:2][CH:1]=2)[N:15]=1

Participants

4

Reactant 2

HCID 49642-Bromo-1-(4-hydroxyphenyl)ethanoneHCID 2723949Thioacetamide

Product 1

HCID 23289284138330-02-6

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

4-(2-Methylthiazol-4-yl)-phenol hydrobromide was prepared from α-bromo-4-hydroxyacetophenone and thioacetamide as described in Preparation 48; m.p. 250-251° C. (CH2Cl2).

Workup

  1. customas described in Preparation 48

Sources & evidence

ORD record
ord-a6c7b88a312e456890a5990db3de5b79
Source dataset
uspto-grants-2000_10
Patent number
US06130217

Reaction notes

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