Hydrochloric Acid → HCID 23284422, compound

HRID 368964Notes

Reaction equation

HRID 368964 reaction equation
[N+:1]([C:4]1[CH:9]=[C:8]([C:10]([F:13])([F:12])[F:11])[C:7](F)=[CH:6][C:5]=1[NH:15][CH2:16][P:17]([OH:20])(=[O:19])[OH:18])([O-:3])=[O:2].C(=O)([O-])[O-].[Na+].[Na+].[C:27]1([OH:33])[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1.Cl>O>[N+:1]([C:4]1[CH:9]=[C:8]([C:10]([F:13])([F:12])[F:11])[C:7]([O:33][C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)=[CH:6][C:5]=1[NH:15][CH2:16][P:17]([OH:20])(=[O:19])[OH:18])([O-:3])=[O:2]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 996PhenolHCID 10340Sodium CarbonateHCID 23284431HCID 23284431, compound

Product 1

HCID 23284422HCID 23284422, compoundYield 68.6%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

) 3.18 g of N-(2-nitro-4-trifluoromethyl-5-fluorophenyl)-aminomethanephosphonic acid is stirred together with 3.18 g of sodium carbonate and 2.82 g of phenol in 40 ml of water for 4 hours at a bath temperature of 120° C. After acidification with 4N hydrochloric acid, the precipitated product is suctioned off. 2.69 g of N-(2-nitro-4-TRIFLUOROMETHYL-5-phenoxyphenyl)-aminomethanephosphonic acid is obtained.

Sources & evidence

ORD record
ord-9536476cb1fb4cdc9d4a758d14eee5e8
Source dataset
uspto-grants-2000_10
Patent number
US06136805

Reaction notes

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