huagongshe.com
HRID369455

反应详情

EQUATION

反应方程式

HRID 369455 的结构方程式

REACTANTS

反应物

2
结构：COC(OC)N(C)C
HCID78373

Methanamine, 1,1-dimethoxy-N,N-dimethyl-

C5H13NO2

结构：CCOC(=O)C(C#N)=C(C)C
HCID136573

2-Butenoic acid, 2-cyano-3-methyl-, ethyl ester

C8H11NO2

PRODUCTS

生成物

1
结构：CCOC(=O)C(C#N)=C(C)C=CN(C)C
HCID54385987

2,4-Pentadienoic acid, 2-cyano-5-(dimethylamino)-3-methyl-, ethyl ester

C11H16N2O2

收率 100%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

A mixture of 127.7 g (0.839 mole) of ethyl isopropylidenecyanoacetate (4) and 100 g (0.839 mole) of N.N-dimethylformamide dimethyl acetal in 500 mL of ethanol was refluxed for 24 hours. The ethanol was removed under reduced pressure to give 124 g (100%) of a dark oil.

WORKUP

后处理

  1. temperaturewas refluxed for 24 hours
  2. customThe ethanol was removed under reduced pressure