反应详情

Under a protective gas, 7.19 g (29 mmol) of 2-amino-3-ethoxycarbonyl-5-(3-methoxy-phenyl)-1H-pyrrole in 59 ml of formamide, 29.5 ml of DMF and 14.7 ml of formic acid are heated at 150° C. overnight. Working-up analogously to Step 8.2 yields the title compound; TLC-Rf =0.3 (hexane/ethyl acetate [1:1]).