Potassium Carbonate → HCID 20275690, compound

HRID 370378Notes

Reaction equation

HRID 370378 reaction equation
[Cl:1][C:2]1[C:3]([O:12][C:13]2[CH:18]=[CH:17][C:16]([N+:19]([O-:21])=[O:20])=[C:15]([N+:22]([O-])=[O:23])[CH:14]=2)=[N:4][CH:5]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:7]=1.[CH3:25]NO.C([O-])([O-])=O.[K+].[K+]>C1COCC1>[CH3:25][N:22]([OH:23])[C:15]1[CH:14]=[C:13]([O:12][C:3]2[C:2]([Cl:1])=[CH:7][C:6]([C:8]([F:10])([F:11])[F:9])=[CH:5][N:4]=2)[CH:18]=[CH:17][C:16]=1[N+:19]([O-:21])=[O:20]

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 11647MethylhydroxylamineHCID 202515733-Chloro-2-(3,4-dinitrophenoxy)-5-(trifluoromethyl)pyridine

Product 1

HCID 20275690HCID 20275690, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

A mixture of 4-(3-chloro-5-trifluoromethyl-2-pyridyloxy)-1,2-dinitrobenzene (2.50 g, 6.88 mmol), N-methylhydroxyamine (1.15 g), K2CO3 (1.14 g, 8.26 mmol) and THF (20 ml) is stirred at RT for 48 hours. The reaction mixture is filtered and the filtrate is concentrated. The resulting residue is taken up in CH2Cl2, washed, dried and evaporated to give N-methyl-N-[2-nitro-5-(3-chloro-5-trifluoromethyl-2-pyridyloxy)phenyl]-hydroxyamine (IXB; R is H).

Workup

  1. filtrationThe reaction mixture is filtered
  2. concentrationthe filtrate is concentrated
  3. washwashed
  4. customdried
  5. customevaporated

Sources & evidence

ORD record
ord-67a5b21ad343499cbf33cb42f1c5b6ac
Source dataset
uspto-grants-1985_07
Patent number
US04526608

Reaction notes

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