Potassium Carbonate → HCID 20275710, compound

HRID 370379Notes

Reaction equation

HRID 370379 reaction equation
[Cl:1][C:2]1[C:3]([O:9][C:10]2[CH:15]=[CH:14][C:13]([N+:16]([O-:18])=[O:17])=[C:12]([N+:19]([O-:21])=O)[CH:11]=2)=[N:4][CH:5]=[C:6]([Cl:8])[CH:7]=1.[CH3:22]NO.C([O-])([O-])=O.[K+].[K+]>C1COCC1>[CH3:22][N:19]([OH:21])[C:12]1[CH:11]=[C:10]([O:9][C:3]2[C:2]([Cl:1])=[CH:7][C:6]([Cl:8])=[CH:5][N:4]=2)[CH:15]=[CH:14][C:13]=1[N+:16]([O-:18])=[O:17]

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 11647MethylhydroxylamineHCID 12774252HCID 12774252, compound

Product 1

HCID 20275710HCID 20275710, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

A mixture of 4-(3,5-dichloro-2-pyridyloxy)-1,2-dinitrobenzene (800 mg, 2.42 mmol), N-methylhydroxyamine (472 mg, 4.84 mmol), K2CO3 (400 mg, 2.90 mmol) and THF (10 ml) is stirred at RT for 48 hours. The reaction mixture is filtered, and the filtrate is concentrated and then taken up in methylene chloride, washed, dried and evaporated to give N-methyl-N-[2-nitro-5-(3,5-dichloro-2-pyridyloxy)phenyl]-hydroxyamine, a crystalline solid.

Workup

  1. filtrationThe reaction mixture is filtered
  2. concentrationthe filtrate is concentrated
  3. washwashed
  4. customdried
  5. customevaporated

Sources & evidence

ORD record
ord-e37940ccf22f4a82bc33d1a632726027
Source dataset
uspto-grants-1985_07
Patent number
US04526608

Reaction notes

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