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HRID370387

反应详情

EQUATION

反应方程式

HRID 370387 的结构方程式

REACTANTS

反应物

3
结构：N#CCc1cccc(Cl)c1
HCID73722

Acetonitrile, (m-chlorophenyl)-

C8H6ClN

结构：CCOC(=O)CC(C)(C)CC(=O)OCC
HCID87314

Pentanedioic acid, 3,3-dimethyl-, diethyl ester

C11H20O4

结构：[Na]
HCID5360545

Sodium

Na

PRODUCTS

生成物

1
结构：CCOC(=O)CC(C)(C)CC(=O)C(C#N)c1cccc(Cl)c1
HCID20275820

未命名化合物

收率 71%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

Starting with 75.0 g (0.495 mol) of 3-chlorobenzyl cyanide, 160.58 g (0.743 mol) of diethyl 3,3-dimethylglutarate, 14.80 g (0.643 mol) of sodium, and 260 ml of dry ethanol a total of 108.08 g (71% yield) of the desired product was obtained using the procedure described in Example I, Part A.