Palmitoyl chloride → HCID 20275854, compound

HRID 370390Notes

Reaction equation

HRID 370390 reaction equation
[CH3:1][C:2]1([CH3:10])[CH2:7][C:6](=[O:8])[CH2:5][C:4](=[O:9])[CH2:3]1.[C:11](Cl)(=[O:27])[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26].C(N([CH2:34][CH3:35])CC)C>C(Cl)Cl>[C:11]([O:8][C:6]1[CH2:7][C:2]([CH3:10])([CH3:1])[CH2:3][C:4](=[O:9])[C:5]=1[C:2]1[CH:7]=[CH:6][C:34]([CH3:35])=[CH:4][CH:3]=1)(=[O:27])[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26]

Participants

5

Reactant 3

HCID 8206Palmitoyl chlorideHCID 8471TriethylamineHCID 31358Dimedone

Product 1

HCID 20275854HCID 20275854, compoundYield 67%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Using the procedure described in Example III and starting with 3.00 g (0.0130 mol) of 2-4'-methylphenyl)-5,5-dimethyl-1,3-cyclohexanedione, 2.69 g (0.0098 mol) of palmitoyl chloride, 2.63 g (0.0260 mol) of triethylamine, and 30 ml of methylene chloride, 3.1 g (67% yield) of a clear, colorless oil was obtained as the desired product.

Sources & evidence

ORD record
ord-f2c4b8b3705f4e20b90c0f8058d290d2
Source dataset
uspto-grants-1985_07
Patent number
US04526723

Reaction notes

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