反应详情

A mixture of 28.5 g of cyclopropylamine and 50.5 g of triethylamine was added drop-by-drop to a stirred solution of 92.3 g of cyanuric chloride in 1.5 liters of dry acetone at room temperature. Then the acetone was evaporated and the residue was treated with a 1:1 v:v mixture of ice water and ether. The ether phase was separated and dried (MgSO4), and the ether was evaporated to give 2-cyclopropyl-4,6-dichloro-1,3,5-triazine (9A), as a white solid, m.p.: 106°-107° C.

1. customThen the acetone was evaporated
2. additionthe residue was treated with a 1:1 v
3. additionv mixture of ice water and ether
4. customThe ether phase was separated
5. dry with materialdried (MgSO4)
6. customthe ether was evaporated