91702-96-4 → HCID 3021853, compound

HRID 370737Notes

Reaction equation

HRID 370737 reaction equation
C([S:4][CH2:5][CH:6]([CH3:20])[C:7]([NH:9][C:10]1[C:11]([C:16]([O:18][CH3:19])=[O:17])=[N:12][CH:13]=[CH:14][CH:15]=1)=[O:8])(=O)C.C(SCC(C)C(NC1N=CC=CC=1C(OC)=O)=O)(=O)C>C(OCC)(=O)C>[SH:4][CH2:5][CH:6]([CH3:20])[C:7]([NH:9][C:10]1[C:11]([C:16]([O:18][CH3:19])=[O:17])=[N:12][CH:13]=[CH:14][CH:15]=1)=[O:8]

Participants

4

Reactant 2

HCID 302185291702-96-4HCID 20275380HCID 20275380, compound

Product 1

HCID 3021853HCID 3021853, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

Following the procedure of Example 2, but substituting an equivalent amount of methyl 3-(2-acetylthiomethyl-propionamido)-picolinate, obtained as disclosed in Example 24, for methyl 2-(2-acetylthiomethyl-propionamido)-nicotinate and using ethyl acetate as eluent for the chromatography column, methyl 3-(2-mercaptomethyl-propionamido)-picolinate is obtained; m.p. 55°-56° C., from petroleum ether.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-e628734838394df48a45102e1cd69a3c
Source dataset
uspto-grants-1985_07
Patent number
US04528296

Reaction notes

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