反应详情

A mixture of 4.8 g. 3-propylsulphinyl-1,2,4-triazole, 6.0 ml. dipropylcarbamoyl chloride, 25 ml. dry tetrahydrofuran and 7.5 ml. dry triethylamine was refluxed under anhydrous conditions for 2 hours. The cooled reaction mixture was filtered and the filtrate distilled under reduced pressure to give an oily residue which crystallized on trituration with petroleum ether (b.p. 60° - 80° C.). The resulting solid product was recrystallized from petroleum ether (b.p. 60° - 80° C.) to give 1-dipropylcarbamoyl-3-propylsulphinyl-1,2,4-triazole, m.p. 50° - 52° C. Elemental analysis satisfactory.

1. additionA mixture of 4.8 g
2. customThe cooled reaction mixture
3. filtrationwas filtered
4. distillationthe filtrate distilled under reduced pressure
5. customto give an oily residue which
6. customcrystallized on trituration with petroleum ether (b.p. 60° - 80° C.)
7. customThe resulting solid product was recrystallized from petroleum ether (b.p. 60° - 80° C.)