Hydrochloric Acid → 2-Pyridinecarbonitrile, 3,5,6-trichloro-4-hydrazino-

HRID 371619Notes

Reaction equation

[Cl:1][C:2]1[C:3]([C:12](O)=O)=[N:4][C:5]([Cl:11])=[C:6]([Cl:10])[C:7]=1[NH:8][NH2:9].ClC1[N:21]=C(C#N)C(Cl)=C(Cl)C=1Cl.NN.Cl>>[Cl:1][C:2]1[C:3]([C:12]#[N:21])=[N:4][C:5]([Cl:11])=[C:6]([Cl:10])[C:7]=1[NH:8][NH2:9]

Participants

Reactant 4

HCID 313Hydrochloric Acid

HCID 9321Hydrazine

HCID 87323Tetrachloropicolinonitrile

HCID 13834393,5,6-Trichloro-4-hydrazinylpyridine-2-carboxylic acid

Product 1

HCID 18986162-Pyridinecarbonitrile, 3,5,6-trichloro-4-hydrazino-

Procedure

The 3,5,6-trichloro-4-hydrazinopicolinic acid can be prepared in a variety of ways. In one such method, tetrachloropicolinonitrile is reacted with hydrazine in the presence of a reaction medium and hydrogen chloride acceptor. The 3,5,6-trichloro-4-hydrazinopicolinonitrile product thus formed is reacted with an acid hydrolysis agent to prepare 3,5,6-trichloro-4-hydrazinopicolinic acid.

Sources & evidence

ORD record: ord-97649d3c115f482aa74d07833af85f6b
Source dataset: uspto-grants-1978_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04087431

Reaction notes

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