Hydrogen Bromide → HCID 19906125, compound

HRID 371698Notes

Reaction equation

HRID 371698 reaction equation
[CH2:1]([NH:4][C:5]([CH2:7][P:8](=[O:12])([O-:11])[O:9]C)=[O:6])[CH2:2][CH3:3].Br>C(O)(=O)C>[CH2:1]([NH:4][C:5]([CH2:7][P:8](=[O:9])([OH:12])[OH:11])=[O:6])[CH2:2][CH3:3]

Participants

4

Reactant 2

HCID 260Hydrogen BromideHCID 86735669HCID 86735669, compound

Product 1

HCID 19906125HCID 19906125, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

1 g. of Monomethyl propylcarbamoylmethylphosphonate was suspended in 10 ml. of hydrogen bromide in glacial acetic acid. The solution was allowed to stand overnight at room temperature. The solution was then concentrated to a viscous oil under reduced pressure. Upon the addition of methanol, the compound crystallized; m.p. 155°-160° C.; yield, 47%.

Workup

  1. concentrationThe solution was then concentrated to a viscous oil under reduced pressure
  2. additionUpon the addition of methanol
  3. customthe compound crystallized
  4. customyield

Sources & evidence

ORD record
ord-ef0ec5d26e04419b88d7a744fa20f896
Source dataset
uspto-grants-1978_05
Patent number
US04087522

Reaction notes

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