Hydrogen Peroxide → HCID 22758561, compound

HRID 372572Notes

Reaction equation

HRID 372572 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:15])[CH:9]=[CH:10][C:11]([NH:13][CH3:14])=[O:12])=[CH:4][CH:3]=1.OO.C(O)(=[O:21])C=C.CN>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]([CH:9]2[O:21][CH:10]2[C:11]([NH:13][CH3:14])=[O:12])=[O:15])=[CH:6][CH:7]=1

Participants

5

Reactant 4

HCID 784Hydrogen PeroxideHCID 6329MethylamineHCID 6581Acrylic AcidHCID 54452974HCID 54452974, compound2×

Product 1

HCID 22758561HCID 22758561, compound

Procedure

3 was prepared as a white solid, m.p.: 160°-161° C, from 4-(4-chlorophenyl)-N-methyl-4-oxo-2-butenamide (3A) by hydrogen peroxide oxidation by the procedure described in Example 1, 3A having been prepared from the corresponding acrylic acid and monomethylamine by the procedure described in Example 2.

Sources & evidence

ORD record
ord-27247c51ce6c48f48a4f793593051327
Source dataset
uspto-grants-1978_05
Patent number
US04091221

Reaction notes

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